Have not gone into deep, however have updated a couple of local and live sites with a few custom and purchased add-ons, so far no issues. Also I always update jQuery to the latest (3.5.1), could you not do the same?

Hope this helps.

P.S If you need a site address, let me know.

The general local/live setup:
# Database Information
Version: 10.3.24-MariaDB-log-cll-lve
SQL Mode: NO_AUTO_CREATE_USER,NO_ENGINE_SUBSTITUTION

# concrete5 Packages
Automatic Email Obfuscator (2.0.1), Blog Module (1.1.2), Box Gallery (1.3), Feature Block (1.0), GDPR Cookie Notice (1.0.1), Login Return (1.0), Orchard Theme (1.0), Parallax Area (2.4.2), Popup Gallery Block (1.1), Quick Tabs (1.0), Video Lightbox (2.5)

# concrete5 Overrides
elements/cart_list.php, single_pages/login.php, single_pages/register.php, single_pages/checkout/complete.php, single_pages/checkout, single_pages/checkout.php, single_pages/cart.php

# concrete5 Cache Settings
Block Cache - Off
Overrides Cache - Off
Full Page Caching - Off
Full Page Cache Lifetime - Every 6 hours (default setting).

# Server Software
LiteSpeed

# Server API
litespeed

# PHP Version
7.4.12

# PHP Extensions
bcmath, bz2, calendar, Core, ctype, curl, date, dom, exif, fileinfo, filter, ftp, gd, gettext, gmp, hash, iconv, imagick, imap, intl, json, libxml, litespeed, mbstring, mysqli, mysqlnd, openssl, pcntl, pcre, PDFlib, PDO, pdo_mysql, pdo_sqlite, Phar, posix, readline, Reflection, session, shmop, SimpleXML, sockets, SPL, sqlite3, standard, timezonedb, tokenizer, xml, xmlreader, xmlrpc, xmlwriter, xsl, Zend OPcache, zip, zlib

# PHP Settings
max_execution_time - 120
log_errors_max_len - 1024
max_file_uploads - 20
max_input_nesting_level - 64
max_input_time - 360
max_input_vars - 8000
memory_limit - 256M
post_max_size - 512M
upload_max_filesize - 512M
mbstring.regex_retry_limit - 1000000
mbstring.regex_stack_limit - 100000
mysqli.max_links - Unlimited
mysqli.max_persistent - Unlimited
pcre.backtrack_limit - 1000000
pcre.recursion_limit - 100000
session.cache_limiter - <i>no value</i>
session.gc_maxlifetime - 7200
unserialize_max_depth - 4096
opcache.max_accelerated_files - 7963
opcache.max_file_size - 0
opcache.max_wasted_percentage - 5